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Symbol
Name
ID 		Tcra-J
T cell receptor alpha, joining region
MGI:98555
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
increased thymocyte number
abnormal T cell differentiation
abnormal T cell receptor alpha chain V-J recombination
increased double-negative T cell number
decreased double-positive T cell number
abnormal eosinophil cell number
decreased B cell number
decreased NK T cell number
decreased activated T cell number
decreased single-positive T cell number
decreased IgE level
decreased IgG level
decreased circulating interferon-gamma level
decreased circulating interleukin-5 level
abnormal immune serum protein physiology
decreased interferon-gamma secretion
abnormal interleukin secretion
decreased interleukin-10 secretion
decreased interleukin-13 secretion
decreased interleukin-17 secretion
decreased interleukin-4 secretion
decreased interleukin-5 secretion
decreased interleukin-9 secretion
decreased susceptibility to induced arthritis
increased incidence of corneal inflammation
liver inflammation
lung inflammation
decreased susceptibility to bacterial infection
Availability Mouse Genotype
Tcra-Jtm1Jpdv/Tcra-Jtm1Jpdv
Tcra-Jtm1Slek/Tcra-Jtm1Slek
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
Tcra-Jtm2.3Krg/Tcra-Jtm2.3Krg
Tcra-Jtm3.1Krg/Tcra-Jtm3.1Krg
Tcra-Jtm4.1Krg/Tcra-Jtm4.1Krg
Tcra-Jtm5Krg/Tcra-Jtm5Krg
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory